Hose down coils on the exterior unit periodically.
Have all units professionally serviced annually.
Never store flammables near your system.
Read and follow all manufacturer instructions.
Maintain the comfort in your home by adjusting the damper and registers, keeping your basement door closed and using blinds on windows. Adjust the damper and registers seasonally.
Do not block supply or return air grills with furniture or other objects.
Make sure fireplace dampers are closed when not in use (unless you have gas logs).